It’s looking increasingly likely that our little bacterial buddies have a major influence on neurodegenerative disease, from producing extra amy...

Merry Media, And A Happy New Year
We want you! Reason over at Fight Aging! lists nine promising approaches to rejuvenation therapy that he’d like to see in the very near future: ...

Video interview with James Peyer: Longevity science from bench to clinic, and everything in between
No one should have to read during the holidays. That’s why we made you a video! I spoke to our own James Peyer about how he got started in the l...

Oxidative stress response: One of the many jobs of tumor-suppressor p53
At its most dramatic, oxidative stress can rend DNA in two and predispose cells to mutations that ultimately result in cancer. But the less bombastic ...

Research roundup: The importance of energy in Alzheimer’s, and more
Since the world of Alzheimer’s therapeutics hasn’t seen much practical benefit from targeting harmful proteins like amyloid-beta, maybe ot...

Evolution eats the old to feed the young
Part II of III in a series on the evolution of aging. (Part I, Part III) Sex and death have been friends for a long time. Many people would tell you t...

In the media: An AMA with Aubrey de Grey, and more
Aubrey de Grey held a Reddit AMA on December 7th, discussing everything from AI in longevity research, CR mimetics, and how his timelines for therapeu...

Could marmosets become the new standard in animal models?
In biomedical science, rodents are the old stalwarts: they’re cheap, easy to care for, have lives short enough to allow us to observe them over the co...

How your ancestors’ lifestyle determines your lifespan
Part I of III in a series on the evolution of aging. (Part II, Part III) Here’s an interesting experiment that I don’t recommend trying at home. Take ...

Research roundup: Tau tangles guilty by association, and more
It looks like those clumps of tau protein that form inside the neurons of Alzheimer’s brains may actually be protective, and the real damage mig...