All cells in your body have the same DNA, yet they express different proteins and do different things. How does that happen? Various alterations in y...
A bountiful harvest of research
Keeping one eye on your calories, and the other on that delicious-looking pumpkin pie? Don’t worry–your Thanksgiving sins probably wonR...
Cheat codes for youthful cells
For much of the 20th century, the prevailing wisdom was that once cells were fully differentiated, their identities were crystallized eternally–...
In the media: Salamanders, supercentenarians and Silicon Valley
Can we “unlock a human’s inner salamander” with stem cell therapies? 3D-printed organs, uploaded brains, and disease-fighting nanobo...
Out with the old, in with the… old?
Researchers at UNC Chapel Hill had an interesting mission: first, transform scar tissue (like the kind that forms after heart attacks) into ordinary c...
Research roundup: Scars into hearts, and more
We can reprogram existing scar tissue into healthy organ tissue, but we didn’t know what was actually going on inside these newly revitalized ce...
Diagnosis: Cursed?
The year is 1996, and you’re a doctor with a strange case on your hands. Actually, it’s not just one case–it’s an entire family with a collectio...
Metformin as Geroprotector
The diabetes drug Metformin is handled as new anti-aging compound. But which studies actually promoted the longevity effects of Metformin? We provide ...
In the media: White papers, worms and “Why die?”
LEAF takes an incisive look at the popular “eternal snoozefest” view of life extension and knocks down that shaky extrapolation from elder...
Michael Fossel on telomerase therapy in cancer, Alzheimer’s, and more
Last week we heard the theoretical side of Dr. Michael Fossel’s mission to bring aging to its knees, and why his chosen point of attack was on t...