At its most dramatic, oxidative stress can rend DNA in two and predispose cells to mutations that ultimately result in cancer. But the less bombastic ...
Research roundup: The importance of energy in Alzheimer’s, and more
Since the world of Alzheimer’s therapeutics hasn’t seen much practical benefit from targeting harmful proteins like amyloid-beta, maybe ot...
Research roundup: Tau tangles guilty by association, and more
It looks like those clumps of tau protein that form inside the neurons of Alzheimer’s brains may actually be protective, and the real damage mig...
Breaking skin: Tiny troublemakers in epidermal aging
That weathered, pruny exterior loved by photographers and loathed by nearly everyone else is, along with gray hair, perhaps the most easily recognizab...
James Peyer: “The 21st century will be defined by our struggle against the diseases of aging.”
“At what age would you like to get Alzheimer’s?” This was the question posed by venture capitalist, former stem cell biologist and G...
The Hallmarks of Aging: Epigenetic Alterations
All cells in your body have the same DNA, yet they express different proteins and do different things. How does that happen? Various alterations in y...
A bountiful harvest of research
Keeping one eye on your calories, and the other on that delicious-looking pumpkin pie? Don’t worry–your Thanksgiving sins probably wonR...
Cheat codes for youthful cells
For much of the 20th century, the prevailing wisdom was that once cells were fully differentiated, their identities were crystallized eternally–...
Michael Fossel on telomerase therapy in cancer, Alzheimer’s, and more
Last week we heard the theoretical side of Dr. Michael Fossel’s mission to bring aging to its knees, and why his chosen point of attack was on t...
Research roundup: The Hippo in your heart, and more
The Hippo pathway controls cellular regeneration, so why not modify it to heal the heart after the scarring caused by a heart attack? Six weeks later,...