Researchers from Houston Methodist Research Institute took cells from patients with progeria, a devastating condition that causes premature aging, and...
Metformin: Multipurpose marvel, or medical misfire?
Much rests on metformin’s shoulders: as the first drug to begin clinical trials for preventing multiple age-related diseases, it could soon become the...
Metformin: Stress versus strength
Imagine pulling a rubber band taut and flicking it with your finger. As long as you don’t flick too hard, the rubber band will always snap back into i...
Metformin: Can you have your cake and eat it, too?
When Americans 50 years ago envisioned the perfect youthful physique, the trim, athletic body would surely have sported a sun-baked complexion. And wh...
The joy of scientific discovery, converging disease mechanisms, and failures of communication: Dr Gordon Lithgow on the past and present of geroscience (part II)
Dr. Gordon Lithgow of the Buck Institute for Research on Aging, who spoke to us recently about the Caenorhabditis Intervention Testing Program, talks ...
Live slow, die old: Mounting evidence for caloric restriction in humans
Let’s say you wanted to hear a first-hand story of ordinary life 100 years ago. Where might you go to find a storyteller? Maybe you want to hear as ma...
TAME: Teaching old diabetes drugs new tricks
In 2014, researchers behind a study comparing two diabetes drugs were surprised to find that not only did patients on one of the medications have high...