That weathered, pruny exterior loved by photographers and loathed by nearly everyone else is, along with gray hair, perhaps the most easily recognizab...
Better together? Testing the first combination therapies for longevity
The normal mode of drug discovery is a pretty singular affair: one compound, one disease. This is enough for many traditional diseases, but when you’r...
Longevity orthologs: How far from the apple to the tree?
Laboratories studying the biology of aging are a menagerie of creatures great and small. From unicellular yeast and nematodes, all the way up to prima...
Research roundup: Scientists stop premature aging in its tracks, and more
Researchers from Houston Methodist Research Institute took cells from patients with progeria, a devastating condition that causes premature aging, and...
Autophagy: Young and hungry
Ever been so hungry you thought you might start gnawing on your own body? Your cells certainly have no qualms with it. Right now, millions of them are...
When cancer was just a twinkle in your epigenome’s eye
A friendly genie appears in a puff of smoke and tells you that you’ll develop cancer 20 years hence. However, he offers to send you back in time to an...
Pet dogs on rapamycin are pictures of health
In the lab, rapamycin is a star geroprotector. In addition to boosting lifespan even when used in late life, it’s also been found specifically t...
Do aging circadian clocks have tricks up their sleeves?
Most lifeforms wrap their lives around a 24 hour wheel that dictates when to rise, when to eat, when to grow, and when to sleep. From its seat in a pa...
Intriguing results for Thioflavin T, but reproducibility is the real winner in CITP
Bolstering results from a 2011 study, a team led by Buck Institute researcher Gordon Lithgow found the compound Thioflavin T to increase the lifespan ...
Flip this epigenome: Making old mice good as new
Scientists at the Salk Institute for Biological Studies knew it could be done in principle–all you had to do to erase the telltale signs of agin...