Part III of III in a series on the evolution of aging. (Part I, Part II) If all you had to go on was our genomes, you’d surely conclude that humans an...
James Peyer: Navigating the “Biotech Valley of Death”
Ever hear about an exciting discovery in the biomedical world, then later wonder why it seemingly dropped off the face of the Earth? In fact, it’...
Are cancer prevention and cellular reprogramming really enemies?
Imagine a physiological love triangle: in one corner, a force with the weight of millions of years of evolutionary programming trained on preventing r...
Can reducing PPAR-γ save the immune system?
One contributor to the aging of your immune system is that your thymus–the gland that turns leukocytes into T cells–is slowly replaced by ...
A peek inside the companies using AI to combat aging
Last Wednesday I attended the Buck Institute’s workshop on AI and Longevity, where speakers from several different organizations discussed how t...
In the media: An AMA with Aubrey de Grey, and more
Aubrey de Grey held a Reddit AMA on December 7th, discussing everything from AI in longevity research, CR mimetics, and how his timelines for therapeu...
Cheat codes for youthful cells
For much of the 20th century, the prevailing wisdom was that once cells were fully differentiated, their identities were crystallized eternally–...
Out with the old, in with the… old?
Researchers at UNC Chapel Hill had an interesting mission: first, transform scar tissue (like the kind that forms after heart attacks) into ordinary c...
Better together? Testing the first combination therapies for longevity
The normal mode of drug discovery is a pretty singular affair: one compound, one disease. This is enough for many traditional diseases, but when you’r...
No more eraserhead: Will blocking epigenetic erasers prevent Alzheimer’s disease?
Just like a well-folded sheet of paper, a tightly coiled segment of DNA doesn’t have much chance of being read. Our cells use this to their advantage,...