Most lifeforms wrap their lives around a 24 hour wheel that dictates when to rise, when to eat, when to grow, and when to sleep. From its seat in a pa...
Intriguing results for Thioflavin T, but reproducibility is the real winner in CITP
Bolstering results from a 2011 study, a team led by Buck Institute researcher Gordon Lithgow found the compound Thioflavin T to increase the lifespan ...
The hallmarks of aging, in plain English
Part of the Hallmarks of Aging series. Did you know you have two different ages? The obvious one is chronological age, or the number of years since yo...
Live slow, die old: Mounting evidence for caloric restriction in humans
Let’s say you wanted to hear a first-hand story of ordinary life 100 years ago. Where might you go to find a storyteller? Maybe you want to hear as ma...
Flip this epigenome: Making old mice good as new
Scientists at the Salk Institute for Biological Studies knew it could be done in principle–all you had to do to erase the telltale signs of agin...
TAME: Teaching old diabetes drugs new tricks
In 2014, researchers behind a study comparing two diabetes drugs were surprised to find that not only did patients on one of the medications have high...
Challenges of developing medicines for aging
Startups developing medicines to slow or prevent the diseases of aging all follow a similar three-step strategy. First they start from data generated ...
Welcome to the (Extracellular) Matrix
An interview with Dr. Collin Ewald Dr. Collin Ewald studies aging with the help of the roundworm C. elegans, an invertebrate with an already illustrio...
Aging Demystified
Modern health and medicine have all but eradicated the poxes and plagues that fixed the life expectancy of a person in the 19th century at 40 years ol...
Interview with Linda Greensmith – A motor neuron expert
Linda Greensmith is a Professor at the Institute of Neurology (IoN), University College London (UCL) and a leading expert for motorneurons. She did h...