Imagine a physiological love triangle: in one corner, a force with the weight of millions of years of evolutionary programming trained on preventing r...

Research roundup: The importance of energy in Alzheimer’s, and more
Since the world of Alzheimer’s therapeutics hasn’t seen much practical benefit from targeting harmful proteins like amyloid-beta, maybe ot...

The Hallmarks of Aging: Epigenetic Alterations
All cells in your body have the same DNA, yet they express different proteins and do different things. How does that happen? Various alterations in y...

A bountiful harvest of research
Keeping one eye on your calories, and the other on that delicious-looking pumpkin pie? Don’t worry–your Thanksgiving sins probably wonR...

Cheat codes for youthful cells
For much of the 20th century, the prevailing wisdom was that once cells were fully differentiated, their identities were crystallized eternally–...

Out with the old, in with the… old?
Researchers at UNC Chapel Hill had an interesting mission: first, transform scar tissue (like the kind that forms after heart attacks) into ordinary c...

Flip this epigenome: Making old mice good as new
Scientists at the Salk Institute for Biological Studies knew it could be done in principle–all you had to do to erase the telltale signs of agin...