Introducing spermidine Present in all mammalian cells, polyamines are positively charged ions that are vital for cellular growth, survival, and divisi...
Using neurodegeneration to fight cancer safely and effectively
The "magic bullet", a universal solution to target all cancer types without harming normal body cells, is what early cancer researchers thought we'd i...
Research roundup: The naked (mole rat) truth, and more
What good is a longer life if you have to spend half of it keeping up with the news? Ditch those endlessly scrolling feeds, and instead join us every ...
Research roundup: The microbiome in neurodegenerative disease, and more
It’s looking increasingly likely that our little bacterial buddies have a major influence on neurodegenerative disease, from producing extra amy...
The Hallmarks of Aging: Loss of Proteostasis
Part of a series on the Hallmarks of Aging. Proteins don’t do everything in your body, but it’s fair to say they control everything. What they don’t d...
FOXO vs. a harbinger of neurodegeneration
Long before the usual physiological signs, the withering of neurons and the gradual atrophy of the brain, that tip doctors off to the presence of a ne...
Research roundup: Untangling ApoE4, and more
It’s been known for ages that individuals with two ApoE4 alleles were virtually destined to develop Alzheimer’s, but its link with the hal...
Longevity orthologs: How far from the apple to the tree?
Laboratories studying the biology of aging are a menagerie of creatures great and small. From unicellular yeast and nematodes, all the way up to prima...
No more eraserhead: Will blocking epigenetic erasers prevent Alzheimer’s disease?
Just like a well-folded sheet of paper, a tightly coiled segment of DNA doesn’t have much chance of being read. Our cells use this to their advantage,...
What’s eating you?
Many people think of sleep almost as if it were a state of suspended animation, like turning off a computer so that it can cool down. But while your c...