Imagine a physiological love triangle: in one corner, a force with the weight of millions of years of evolutionary programming trained on preventing r...
Research roundup: The microbiome in neurodegenerative disease, and more
It’s looking increasingly likely that our little bacterial buddies have a major influence on neurodegenerative disease, from producing extra amy...
Evolution eats the old to feed the young
Part II of III in a series on the evolution of aging. (Part I, Part III) Sex and death have been friends for a long time. Many people would tell you t...
The Aging Immune System
The immune system degrades as we age. The elderly get sick more often, take longer to recover from illness or injury, are more prone to cancer, and mo...
Research roundup: The Hippo in your heart, and more
The Hippo pathway controls cellular regeneration, so why not modify it to heal the heart after the scarring caused by a heart attack? Six weeks later,...
Research roundup: Untangling ApoE4, and more
It’s been known for ages that individuals with two ApoE4 alleles were virtually destined to develop Alzheimer’s, but its link with the hal...
Metformin: Can you have your cake and eat it, too?
When Americans 50 years ago envisioned the perfect youthful physique, the trim, athletic body would surely have sported a sun-baked complexion. And wh...
The hallmarks of aging, in plain English
Part of the Hallmarks of Aging series. Did you know you have two different ages? The obvious one is chronological age, or the number of years since yo...
Live slow, die old: Mounting evidence for caloric restriction in humans
Let’s say you wanted to hear a first-hand story of ordinary life 100 years ago. Where might you go to find a storyteller? Maybe you want to hear as ma...
TAME: Teaching old diabetes drugs new tricks
In 2014, researchers behind a study comparing two diabetes drugs were surprised to find that not only did patients on one of the medications have high...