It’s looking increasingly likely that our little bacterial buddies have a major influence on neurodegenerative disease, from producing extra amy...

The Aging Immune System
The immune system degrades as we age. The elderly get sick more often, take longer to recover from illness or injury, are more prone to cancer, and mo...

In the media: Salamanders, supercentenarians and Silicon Valley
Can we “unlock a human’s inner salamander” with stem cell therapies? 3D-printed organs, uploaded brains, and disease-fighting nanobo...

Out with the old, in with the… old?
Researchers at UNC Chapel Hill had an interesting mission: first, transform scar tissue (like the kind that forms after heart attacks) into ordinary c...

Research roundup: Drifters in your epigenome, and more
Epigenetic markers “drift” as we age to cause unintended gene expression changes, but you might be able to slow this via caloric restricti...

Research roundup: Growth hormone receptor mutations in centenarians, and more
A study of centenarians finds a certain mutation of the growth hormone receptor gene is more common among men, but not women, compared to 70-year-old ...

Metformin: Can you have your cake and eat it, too?
When Americans 50 years ago envisioned the perfect youthful physique, the trim, athletic body would surely have sported a sun-baked complexion. And wh...

Your DNA ages too: Genomic instability as a hallmark of aging
Part of the Hallmarks of Aging series. The cells in our bodies are constantly churning out proteins and other structures, built according to the bluep...

The hallmarks of aging, in plain English
Part of the Hallmarks of Aging series. Did you know you have two different ages? The obvious one is chronological age, or the number of years since yo...