Sebastian Aguiar, geroscientist and Venture Fellow at Apollo Ventures, delivers the Lord Florey Lecture at Lincoln College, Oxford in November 2018. H...

Free radicals are not your enemy | An interview with Dr. Michael Ristow (part i)
Dr. Michael Ristow, a professor of energy metabolism at ETH Zurich, bases much of his research into aging on a premise that many of us will find surpr...

Evolution: Pulling doubled lifespan out of a hat
Part III of III in a series on the evolution of aging. (Part I, Part II) If all you had to go on was our genomes, you’d surely conclude that humans an...

Evolution eats the old to feed the young
Part II of III in a series on the evolution of aging. (Part I, Part III) Sex and death have been friends for a long time. Many people would tell you t...

How your ancestors’ lifestyle determines your lifespan
Part I of III in a series on the evolution of aging. (Part II, Part III) Here’s an interesting experiment that I don’t recommend trying at home. Take ...

Longevity orthologs: How far from the apple to the tree?
Laboratories studying the biology of aging are a menagerie of creatures great and small. From unicellular yeast and nematodes, all the way up to prima...

What’s eating you?
Many people think of sleep almost as if it were a state of suspended animation, like turning off a computer so that it can cool down. But while your c...

Autophagy: Young and hungry
Ever been so hungry you thought you might start gnawing on your own body? Your cells certainly have no qualms with it. Right now, millions of them are...

When cancer was just a twinkle in your epigenome’s eye
A friendly genie appears in a puff of smoke and tells you that you’ll develop cancer 20 years hence. However, he offers to send you back in time to an...

Healthspan: Is life extension a Faustian bargain?
If you could buy a few more years of life by sacrificing some of your health, would you? When would the trade stop being worth it to you–when yo...