Can we “unlock a human’s inner salamander” with stem cell therapies? 3D-printed organs, uploaded brains, and disease-fighting nanobo...
Research roundup: Scars into hearts, and more
We can reprogram existing scar tissue into healthy organ tissue, but we didn’t know what was actually going on inside these newly revitalized ce...
Diagnosis: Cursed?
The year is 1996, and you’re a doctor with a strange case on your hands. Actually, it’s not just one case–it’s an entire family with a collectio...
In the media: White papers, worms and “Why die?”
LEAF takes an incisive look at the popular “eternal snoozefest” view of life extension and knocks down that shaky extrapolation from elder...
Michael Fossel on telomerase therapy in cancer, Alzheimer’s, and more
Last week we heard the theoretical side of Dr. Michael Fossel’s mission to bring aging to its knees, and why his chosen point of attack was on t...
Research roundup: The Hippo in your heart, and more
The Hippo pathway controls cellular regeneration, so why not modify it to heal the heart after the scarring caused by a heart attack? Six weeks later,...
Più mosso, Maestro! An interview in the key of telomere with Dr. Michael Fossel
With three decades of experience as a professor of clinical medicine under his belt, Dr. Michael Fossel takes a fundamentally pragmatic approach to ta...
In the media: Telomeres, translation, and treatment
“All of this time I had been thinking about telomere maintenance in terms of the minuscule cellular molecular structures that they are, and the ...
The Hallmarks of Aging: Telomere Attrition
Part of the Hallmarks of Aging series. What–and why–are telomeres? The chromosomes that store your genetic information are capped at each ...
Research roundup: Untangling ApoE4, and more
It’s been known for ages that individuals with two ApoE4 alleles were virtually destined to develop Alzheimer’s, but its link with the hal...